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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ITSN1 All Species: 27.27
Human Site: S516 Identified Species: 75
UniProt: Q15811 Number Species: 8
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q15811 NP_001001132.1 1721 195422 S516 E I E S T N K S R E L R I A E
Chimpanzee Pan troglodytes XP_001166935 1721 195424 S516 E I E S T N K S R E L R I A E
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_848967 1721 195215 S516 E I E S T N K S R E L R I A E
Cat Felis silvestris
Mouse Mus musculus Q9Z0R4 1714 194267 S515 E I E S T N K S R E L R I A E
Rat Rattus norvegicus Q9WVE9 1217 137136 Q227 S S R L K Y R Q L F N S H D K
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001512411 1723 194923 S516 E I E S T N K S R E L R I A E
Chicken Gallus gallus XP_416715 1716 194993 S515 E I E S T N K S R E L R I A E
Frog Xenopus laevis O42287 1270 143652 L280 L T A E E F I L A M H L I D V
Zebra Danio Brachydanio rerio NP_997065 1721 194097 T491 E I E T T N K T R E L R I A E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.8 N.A. 97.2 N.A. 94.5 65.4 N.A. 90 92.9 60.5 77.6 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 99.8 N.A. 98.7 N.A. 96.8 67.7 N.A. 93.8 96.2 66.3 85.4 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 N.A. 100 N.A. 100 0 N.A. 100 100 6.6 86.6 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 N.A. 100 N.A. 100 13.3 N.A. 100 100 6.6 100 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 12 0 0 0 0 0 12 0 0 0 0 78 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 23 0 % D
% Glu: 78 0 78 12 12 0 0 0 0 78 0 0 0 0 78 % E
% Phe: 0 0 0 0 0 12 0 0 0 12 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 12 0 12 0 0 % H
% Ile: 0 78 0 0 0 0 12 0 0 0 0 0 89 0 0 % I
% Lys: 0 0 0 0 12 0 78 0 0 0 0 0 0 0 12 % K
% Leu: 12 0 0 12 0 0 0 12 12 0 78 12 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 12 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 78 0 0 0 0 12 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 12 0 0 0 0 0 0 0 % Q
% Arg: 0 0 12 0 0 0 12 0 78 0 0 78 0 0 0 % R
% Ser: 12 12 0 67 0 0 0 67 0 0 0 12 0 0 0 % S
% Thr: 0 12 0 12 78 0 0 12 0 0 0 0 0 0 0 % T
% Val: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 12 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 12 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _